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You Can Get Your Whole Genome Sequenced. But Should You? | WIRED

You Can Get Your Whole Genome Sequenced. But Should You? | WIRED: To find out, primary care doc Jason Vassy recruited a handful of colleagues from around Boston to sequence the full genomes of 50 patients—the first randomized trial of whole genome sequencing in primary care. They expected to find maybe one person with a marker for one of those rare, monogenic diseases. Instead, they found 11. “That’s a shockingly high number,” says Vassy. “If you look at the list of the conditions we found, most primary care physicians have never heard of them. It would would be crazy to think that 20 percent of people have a disease like that.”

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